Too many medications for fibromyalgia just don’t work. There are so many medications for fibromyalgia, and while they all work for a small percentage of those living with the illness, too many don’t work for the vast majority of those living with fibromyalgia.
For all that the drugs have done for Fibromyalgia (FM), the evidence suggests that none of these drugs are particularly helpful for many people with FM. Dr. John Quintner of the National Pain Report points out that the Number Needed to Treat (NNT) for Lyrica indicates that only one out of ten FM patients taking Lyrica is likely to receive a fifty percent or greater reduction in pain. It’s one out of six for Cymbalta and one out of eight for Savella. That means only a small percentage of FM patients can expect their pain levels to drop really significantly on these drugs. via Prohealth.com
I’ve tried them all, you probably have too. The three major drugs approved for Fibromyalgia: Lyrica, Cymbalta, & Savella.
I’ve always understood that for a drug to get approved it has to help 50% of the people 50% of the time (basically if half of the people see a 50% reduction in whatever symptom, it can get approved). According to Dr. John Quintner at the National Pain Report, the reality is much worse.
Of course, medical studies to approve medications typically do not include a diverse group of patients. There are good reasons to keep the patient group as similar as possible. The problem is that the reality of the patients used to test a medication and the patients who actually end up taking that medication are vastly different.
According to Dr. Quintner, the number of patients who are helped even a fraction of the time are often as low as 1 in 10.
This means that only one out of 10 patients taking Lyrica (Preglabin) will have pain relief of 50% or more. Only one out of 6 taking Cymbalta (Duloxetine) will have relief of pain and only about one out of 8 taking Savella (Milnacipran). –National Pain Report
Outside of the main three approved medications for fibromyalgia, there are many others that are used off-label by doctors to treat various symptoms. Unfortunately, they typically work at about the same rate.
I had no luck at all with the Big 3. I think the longest I lasted on any of them was about six months (for both Savella and Cymbalta) before the side effects became intolerable. I didn’t last a week on Lyrica. The improvement I did get from Savella and Cymbalta was minimal. The only med I’ve seen any real improvement with is Gabapentin (Neurontin), the older cousin of Lyrica. It seems to help my nerve pain. After more than a decade this is the only fibromyalgia medication I still take.
Medical marijuana for fibromyalgia
I often wonder why and how they can get away with marketing medications that show so little real improvement. The reality is that the likelihood of getting relief from one of these meds is not much higher than that of a placebo. Yet, so many medications remain unavailable that have shown much stronger efficacy. Medical Marijuana is one such drug, that has been shown repeatedly to reduce symptoms of fibromyalgia, yet it is still not widely available.
The number of states that have legalized medical marijuana continues to grow each year, leaving us hopeful that perhaps we will see it fully legalized within the next decade. As of this update, medical marijuana is fully legal in 36 states; of course, it’s used illegally in the remaining 14.
The 2018 Farm Bill brought us the the widespread legalization of everything made from hemp, including CBD oil, and Delta 8 THC. Both elements can provide the benefits that you see with marijuana in a form that is legal in most states.
CBD is one component of marijuana and can help with some symptoms without the high that is often associated with marijuana. I’ve been taking CBD for several years now and I have found that it helps me sleep well at night and also reduces anxiety during the day.
Delta-8 THC is the trace amounts of THC found in the hemp plant. Since legalization many CBD companies have found ways to extract these small amounts of THC and process them in such a way that they can be consumed in any of the same ways other forms of marijuana are taken. This type of THC typically has less side effects, while, for some, providing more benefit than Delta-9 THC (the form found in marijuana).Too many meds for #fibromyalgia just don't work for most patients. What have you found to successfully treat your symptoms? Click To Tweet
So, what say you? Have you tried medical marijuana? Does it work for you? What medications for Fibromyalgia have you tried that actually worked? (Share your thoughts in the comments below).
- Evaluating the Effects of Lyrica for Fibromyalgia
- Medical Marijuana and Chronic Pain
- Cymbalta Side Effects (Sweating, Flushing, and more)
- Marijuana for Fibromyalgia: Does it work?